diff --git a/plugins/SliceInfoPlugin/SliceInfo.py b/plugins/SliceInfoPlugin/SliceInfo.py
index 2e9e557c4a..fd58e68938 100755
--- a/plugins/SliceInfoPlugin/SliceInfo.py
+++ b/plugins/SliceInfoPlugin/SliceInfo.py
@@ -5,6 +5,7 @@ import json
 import os
 import platform
 import time
+from typing import cast, Optional, Set
 
 from PyQt5.QtCore import pyqtSlot, QObject
 
@@ -16,7 +17,7 @@ from UM.i18n import i18nCatalog
 from UM.Logger import Logger
 from UM.PluginRegistry import PluginRegistry
 from UM.Qt.Duration import DurationFormat
-from typing import cast, Optional
+
 from .SliceInfoJob import SliceInfoJob
 
 
@@ -95,13 +96,29 @@ class SliceInfo(QObject, Extension):
     def setSendSliceInfo(self, enabled: bool):
         Application.getInstance().getPreferences().setValue("info/send_slice_info", enabled)
 
+    def _getUserModifiedSettingKeys(self) -> list:
+        from cura.CuraApplication import CuraApplication
+        application = cast(CuraApplication, Application.getInstance())
+        machine_manager = application.getMachineManager()
+        global_stack = machine_manager.activeMachine
+
+        user_modified_setting_keys = set()  # type: Set[str]
+
+        for stack in [global_stack] + list(global_stack.extruders.values()):
+            # Get all settings in user_changes and quality_changes
+            all_keys = stack.userChanges.getAllKeys() | stack.qualityChanges.getAllKeys()
+            user_modified_setting_keys |= all_keys
+
+        return list(sorted(user_modified_setting_keys))
+
     def _onWriteStarted(self, output_device):
         try:
             if not Application.getInstance().getPreferences().getValue("info/send_slice_info"):
                 Logger.log("d", "'info/send_slice_info' is turned off.")
                 return  # Do nothing, user does not want to send data
 
-            application = Application.getInstance()
+            from cura.CuraApplication import CuraApplication
+            application = cast(CuraApplication, Application.getInstance())
             machine_manager = application.getMachineManager()
             print_information = application.getPrintInformation()
 
@@ -164,6 +181,8 @@ class SliceInfo(QObject, Extension):
 
             data["quality_profile"] = global_stack.quality.getMetaData().get("quality_type")
 
+            data["user_modified_setting_keys"] = self._getUserModifiedSettingKeys()
+
             data["models"] = []
             # Listing all files placed on the build plate
             for node in DepthFirstIterator(application.getController().getScene().getRoot()):
diff --git a/plugins/SliceInfoPlugin/example_data.json b/plugins/SliceInfoPlugin/example_data.json
index ec953e0842..5fc4175e60 100644
--- a/plugins/SliceInfoPlugin/example_data.json
+++ b/plugins/SliceInfoPlugin/example_data.json
@@ -56,6 +56,7 @@
         }
     ],
     "quality_profile": "fast",
+    "user_modified_setting_keys": ["layer_height", "wall_line_width", "infill_sparse_density"],
     "models": [
         {
             "hash": "b72789b9beb5366dff20b1cf501020c3d4d4df7dc2295ecd0fddd0a6436df070",