diff --git a/src/PrusaSlicer.cpp b/src/PrusaSlicer.cpp
index 07fefd0585..881230ff59 100644
--- a/src/PrusaSlicer.cpp
+++ b/src/PrusaSlicer.cpp
@@ -751,6 +751,11 @@ int CLI::run(int argc, char **argv)
         params.load_configs = load_configs;
         params.extra_config = std::move(m_extra_config);
         params.input_files  = std::move(m_input_files);
+        if (has_config_from_profiles && params.input_files.empty()) {
+            params.selected_presets = Slic3r::GUI::CLISelectedProfiles{ m_config.opt_string("print-profile"),
+                                                                        m_config.opt_string("printer-profile") ,
+                                                                        m_config.option<ConfigOptionStrings>("material-profile")->values };
+        }
         params.start_as_gcodeviewer = start_as_gcodeviewer;
         params.start_downloader = start_downloader;
         params.download_url = download_url;
diff --git a/src/slic3r/GUI/GUI_App.cpp b/src/slic3r/GUI/GUI_App.cpp
index ac106ed288..5b2782c5ed 100644
--- a/src/slic3r/GUI/GUI_App.cpp
+++ b/src/slic3r/GUI/GUI_App.cpp
@@ -817,6 +817,26 @@ void GUI_App::post_init()
         }
         if (! this->init_params->extra_config.empty())
             this->mainframe->load_config(this->init_params->extra_config);
+
+        if (this->init_params->selected_presets.has_valid_data()) {
+            if (Tab* printer_tab = get_tab(Preset::TYPE_PRINTER))
+                printer_tab->select_preset(this->init_params->selected_presets.printer);
+
+            const bool is_fff = preset_bundle->printers.get_selected_preset().printer_technology() == ptFFF;
+            if (Tab* print_tab = get_tab(is_fff ? Preset::TYPE_PRINT : Preset::TYPE_SLA_PRINT))
+                print_tab->select_preset(this->init_params->selected_presets.print);
+
+            if (Tab* print_tab = get_tab(is_fff ? Preset::TYPE_FILAMENT : Preset::TYPE_SLA_MATERIAL)) {
+                const auto& materials = this->init_params->selected_presets.materials;
+                print_tab->select_preset(materials[0]);
+
+                if (is_fff && materials.size() > 1) {
+                    for (size_t idx = 1; idx < materials.size(); idx++)
+                        preset_bundle->set_filament_preset(idx, materials[idx]);
+                    sidebar().update_all_filament_comboboxes();
+                }
+            }
+        }
     }
 
     // show "Did you know" notification
diff --git a/src/slic3r/GUI/GUI_Init.hpp b/src/slic3r/GUI/GUI_Init.hpp
index ee1773cf89..2a8e210e65 100644
--- a/src/slic3r/GUI/GUI_Init.hpp
+++ b/src/slic3r/GUI/GUI_Init.hpp
@@ -17,6 +17,15 @@ struct OpenGLVersions
 	static const std::vector<std::pair<int, int>> core;
 };
 
+struct CLISelectedProfiles
+{
+    std::string                 print;
+    std::string                 printer;
+    std::vector<std::string>    materials;
+
+    bool has_valid_data() { return !print.empty() && !printer.empty() && !materials.empty(); }
+};
+
 struct GUI_InitParams
 {
 	int		                    argc;
@@ -28,6 +37,7 @@ struct GUI_InitParams
     std::vector<std::string>    load_configs;
     DynamicPrintConfig          extra_config;
     std::vector<std::string>    input_files;
+    CLISelectedProfiles         selected_presets;
 
     bool                        start_as_gcodeviewer;
     bool                        start_downloader;
diff --git a/src/slic3r/GUI/Sidebar.cpp b/src/slic3r/GUI/Sidebar.cpp
index 635db4afec..7c929c2b78 100644
--- a/src/slic3r/GUI/Sidebar.cpp
+++ b/src/slic3r/GUI/Sidebar.cpp
@@ -587,6 +587,12 @@ void Sidebar::remove_unused_filament_combos(const size_t current_extruder_count)
     }
 }
 
+void Sidebar::update_all_filament_comboboxes()
+{
+    for (PlaterPresetComboBox* cb : m_combos_filament)
+        cb->update();
+}
+
 void Sidebar::update_all_preset_comboboxes()
 {
     PresetBundle &preset_bundle = *wxGetApp().preset_bundle;
@@ -604,8 +610,7 @@ void Sidebar::update_all_preset_comboboxes()
     // Update the filament choosers to only contain the compatible presets, update the color preview,
     // update the dirty flags.
     if (print_tech == ptFFF) {
-        for (PlaterPresetComboBox* cb : m_combos_filament)
-            cb->update();
+        update_all_filament_comboboxes();
     }
 }
 
diff --git a/src/slic3r/GUI/Sidebar.hpp b/src/slic3r/GUI/Sidebar.hpp
index 40d68395f9..31acbe0a96 100644
--- a/src/slic3r/GUI/Sidebar.hpp
+++ b/src/slic3r/GUI/Sidebar.hpp
@@ -135,6 +135,7 @@ public:
     void update_objects_list_extruder_column(size_t extruders_count);
     void update_presets(Preset::Type preset_type);
     void update_printer_presets_combobox();
+    void update_all_filament_comboboxes();
 
     void msw_rescale();
     void sys_color_changed();