diff --git a/src/slic3r/GUI/MainFrame.cpp b/src/slic3r/GUI/MainFrame.cpp
index de640d7b8..a53322914 100644
--- a/src/slic3r/GUI/MainFrame.cpp
+++ b/src/slic3r/GUI/MainFrame.cpp
@@ -353,8 +353,8 @@ void MainFrame::update_layout()
 #endif //__WXMSW__
 
     m_layout = layout;
-
-    m_layerpreview_menu_item->Enable(m_layout == ESettingsLayout::Tabs || m_layout == ESettingsLayout::Old);
+    if (m_plater && m_layerpreview_menu_item)
+        m_layerpreview_menu_item->Enable(m_layout == ESettingsLayout::Tabs || m_layout == ESettingsLayout::Old);
 
     // From the very beginning the Print settings should be selected
     m_last_selected_setting_tab = 0;
diff --git a/src/slic3r/GUI/MainFrame.hpp b/src/slic3r/GUI/MainFrame.hpp
index cc965ce52..2f9a11e3b 100644
--- a/src/slic3r/GUI/MainFrame.hpp
+++ b/src/slic3r/GUI/MainFrame.hpp
@@ -118,7 +118,7 @@ class MainFrame : public DPIFrame
 
     // vector of a MenuBar items changeable in respect to printer technology 
     std::vector<wxMenuItem*> m_changeable_menu_items;
-    wxMenuItem* m_layerpreview_menu_item;
+    wxMenuItem* m_layerpreview_menu_item = nullptr;
 
     wxFileHistory m_recent_projects;